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The multifaceted contributions of mitochondria to cellular metabolism

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These morphologic findings correlate with an early selective depolarization of the resting membrane potentiation, attributed to a decrease in the activity of the electrogenic Na + /K + -ATPase, that results in an enhancement of the efficacy of excitatory inputs to these interneurons (Ross and Soltesz, 2000)

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In addition, many genetic risk factors for PD participate in normal lipid metabolism and function

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