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It serves as the cofactor for several antioxidant enzymes

Glucocorticoids induce a near-total suppression of hyaluronan synthase mRNA in dermal fibroblasts and in osteoblasts: a molecular mechanism contributing to organ atrophy

The extensive research foundation provides solid support for continued investigation in controlled laboratory environments

Clinical studies also support the neuroprotective potential of ALA

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By administering it intratympanicly, as near to the round window as possible, the inner ears bioavailability is enhanced, and the negative consequences of systemic administration are avoided (Fujimoto and Yamasoba 2019)