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In the development of liver fibrosis and cirrhosis, amino acid metabolic reprogramming plays multiple key roles, which not only participates in the systemic energy adaptation of the disease state, but also directly regulates the progression and reversal of fibrosis through specific mechanisms [125]

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Collectively, the combination of treatment based on PDT, SDT, and CDT promoted the accumulation of highly poisonous 1 O 2 and OH, thus producing a drastically powerful anticancer effect

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In vitro studies have reported that this oligonucleotide restores the expression of the cyclin-dependent kinase inhibitor p16 (-CDKN2A) through suppression of DNMT1 expression

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