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The normal cellular function of C9orf72 is related to vesicular trafficking and autophagy (Farg et al., 2014) whereas SOD1 is an antioxidant enzyme that mediates detoxification of the superoxide anion radical (
doi: 10.1046/j.1523-1755.1999.00798.x 79 FrystykJDjurhuusCBJohansenTLangeMSmidtKChristiansenJS
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The glutathione pathway may also supply glutamate when glia-derived glutamine is blocked by MeAIB, which inhibits system A transporters
Eur J Clin Nutr
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