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The evidence for consumption above 2000 mg/day is insufficient for a confident assessment of long-term safety, despite the fact that far greater amounts have been tested without adverse effects and may be safe

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ALC also is involved in regulating gene activity (epigenetics) and is a versatile protective nutrient for the nervous system.

These data indicate that NO-associated redox reactions occurring in the mitochondria play an important role in ASD, although the exact mechanisms implicating NO in this role need further investigation

The established Observed Safe Level (OSL) for chronic, long-term supplementation is generally recognized as 2,000 mg per day, though higher doses have been used safely in monitored trials

Symptom-specific percentages reflect mentions among reviewers who gave 4 or 5 stars