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Pb consistently reduces stimulated glutamate release in several brain regions, including the hippocampus and cortex, likely through disrupted Ca 2+ -dependent mechanisms

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(949) Akhondzadeh, S

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Flores, N

7.6.1 Strategic research priorities Future research should prioritize expanding multi-omics approaches for comprehensive exposure assessment, investigating cumulative and mixture effects to refine risk predictions, validating transgenerational epigenetic inheritance in human cohorts, developing targeted interventions for mitigating EED-induced reproductive damage, and establishing international regulatory standards for exposure limits and safety assessment