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The stuff about nitric oxide and blood vessel function made sense to me from a biological standpoint

However, the research has limitations, including variability in study designs and results, so caregivers should temper expectations and avoid over-relying on supplements as sole interventions

Both are shown to broadly promote angiogenesis, combat oxidative stress, and stimulate cell migration [3, 9, 13]

Never use tap water

doi: 10.3748/wjg.v30.i22.2923

They concluded that "caution should be taken when considering vitamin B12 supplementation in the absence of a vitamin B12 deficiency." Researchers found that combined supplementation of folic acid, vitamin B6, and vitamin B12 was associated with poor renal function and an increase in vascular events in patients with diabetic nephropathy