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Allosteric regulation of ARs transcriptional activity The mechanistic insights reported above are consistent with allosteric regulation of transcription factor action, in which the type of DNA motif to which the factor binds and its protein and ligand interactions influence its conformational plasticity and the availability of tunable multimerization and protein interaction surfaces that control context-dependent and gene-specific transcriptional activity [78, 80]

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Source: European Urology Published online: doi.org/10.1016/j.eururo.2018.12.022 Benefits of Empiric Nutritional and Medical Therapy for Semen Parameters and Pregnancy and Live Birth Rates in Couples with Idiopathic Infertility: A Systematic Review and Meta-analysis. Authors: Muhammad Imran Omar et al.

The inflammation patterns in chronic hepatitis B are not specific and may show significant overlap with other causes of chronic hepatitis, such as hepatitis C, autoimmune hepatitis, or drug effects