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an inhibitor of transcription: implications, problems and solutions

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The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice

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pylori activates host macrophages and gastric epithelial cells through its cell wall components (such as lipopolysaccharides and peptidoglycans) and various toxic molecules, inducing the release of inflammatory mediators such as tumor necrosis factor- ( TNF- ), interleukin ( IL-1 , IL-6 , IL-8 ), thereby initiating the innate immune response [21]

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Interestingly, their analysis demonstrated that different GS-like enzymes accepted various alternate nucleophiles, including d-serine, non-natural amino acids, and alpha-amino alcohols, to yield a range of glutathione variants, but did not produce either serine- or glutamate-substituted analogs

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