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10.1212/WNL.0000000000007047 Neurology 15 DnderA.CaferV.YilmazA.AslanhanH.ArikanoluA

Jarosz M, Dzieniszewski J, Dabrowska-Ufniarz E, Wartanowicz M, Ziemlanski S, Reed PI

This may stress the fact that the efficacy of curcumin may also depend on the administration route (e.g., locally administered through enemas) or the administration form (e.g., using more bioavailable products) (126)

FIGURE 1 2.2 GSHs role in brain-resident immune cells In the CNS, GSH protects mitochondrial function, prevents lipid peroxidation, and maintains the redox state of cysteine residues in proteins

Oral B12 supplements are typically effective, though in some cases sublingual (sprays) or injectable forms may be recommended

Caruso P, Dunmore BJ, Schlosser K, Schoors S, Dos Santos C, Perez-Iratxeta C, et al