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Statements Author contributions JQ and ZY guided the scope and research background of the research, and wrote the manuscript

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Although HSP90 inhibition results in the destabilization of certain proteins such as Ras 32 , the steady-state protein level of BRD4 in the absence of MZ1 was not decreased by either PERK or HSP90 inhibition (Fig

Lin YC, Niewiadomski P, Lin B, Nakamura H, Phua SC, Jiao J, et al

Below are some key clinical applications and treatments targeting GABA and glutamate dysfunctions

These redox imbalances also impact astrocytes, which normally synthesize GSH through the consecutive sections of two ATP consuming cytosolic enzymes