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Pregnant women, individuals with kidney disease, or severe heart conditions should consult a doctor before treatment

NNMT takes nicotinamide, a form of vitamin B3, and attaches a methyl group to it, using SAM (S-adenosylmethionine) as the methyl donor

In addition to metallothioneins, antioxidant enzymes and small molecule antioxidants also provide important defenses against metal toxicity

It is based on the mathematical analysis and visual representation of the interaction between complex variables, which has the advantage of not having to rely on previous assumptions about the relationship among variables and allowing visualization of the association patterns of different variables (23)

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