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ISBN 978-0-471-52693-3

The increased ROS generation and mitochondrial activity are the results of the high metabolic needs of the cochlea, particularly in the sensory hair cells and stria vascularis [23]

Sacubitril is selectively activated by carboxylesterase 1 (CES1) in the liver and the activation is affected by CES1 genetic variation

Endocrinology 151 , 46784687 (2010)

doi: 10.1007/S40520-020-01616-X 216 FissiSGoriERomoliniA
