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glutathione conjugation metabolism of to a generic xenobiotic (X) via catalysis by Oxidative metabolism and glutathione conjugation
Description
Antioxidants (Basel, Switzerland), 2021, 10(12):1864

Chemical peels, laser resurfacing treatments, and products that are designed to lighten areas of hyperpigmented skin can all lead to the thinning of the skin

10.1039/c2cc17013b 10.1039/c2cc17013b [DOI] [PubMed] [Google Scholar] Mueller S, Riedel HD, Stremmel W (1997) Direct evidence for catalase as the predominant H2O2 -removing enzyme in human erythrocytes

Globus MY-T, Busto R, Dietrich WD et al (1988) Intra-ischemic extracellular release of dopamine and glutamate is associated with striatal vulnerability to ischemia

have no relevant financial or non-financial interests to disclose

Furthermore, Nrf2/HO-1 interacts with the NF-KB and JAK-STAT pathways in various contexts: Nrf2/HO-1 can reduce NF-KB phosphorylation and thereby dampen inflammation, whereas proinflammatory cytokines such as TNF- and IL-6, released following NF-KB activation, upregulate HO-1 in a feedback loop (125, 129)