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doi:10.1136/heartjnl-2015-308826 Israr MZ, Bernieh D, Salzano A, et al
Is IL-6 the best pro-inflammatory biomarker of clinical outcomes of cancer cachexia
Weight of evidence: Overall evidence is ModerateLow : encouraging signal from a historical cross-over trial but limited by small samples and lack of biomarker data
Future studies should investigate whether the signal peptide is required for the endogenous function of SFP-1 in males
doi: 10.1097/00005344-199505000-00013
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