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Description
The titration protocol (starting at 2 mg and increasing every four weeks) is essential for tolerability
A daily dose of 350-1000mcg is recommended for most bariatric patients

Patients who are CYP2C19 poor metabolizers (more common in Asian populations: approximately 1520%) have significantly higher and more prolonged plasma Esomeprazole levels due to reduced hepatic metabolism

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Compliance note

Since synthetic vitamins were first used in the late 1930s, humankind has undergone the most massive increase in vitamin use in history
