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TFAM is almost exclusively present in a DNA-bound form (Takamatsu et al., 2002), and degradation of TFAM proteins by mitochondrial matrix proteases directly affects mtDNA copy number (Matsushima et al., 2010)
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The protein concentration (ug/mL) was then determined using a bicinchoninic acid assay
IGF-1 and cardiometabolic diseases: a mendelian zrandomization study
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Vz: The apparent volume of distribution
