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This dual pharmacology was achieved through iterative structure-activity relationship studies that balanced the competing requirements of GIP receptor affinity, GLP-1 receptor activation, and resistance to DPP-4 degradation

K.TruaxA
Haptoglobin alters oxygenation and oxidation of hemoglobin and decreases propagation of peroxide-induced oxidative reactions

Stanley CA

Substantial evidence suggests that endothelial dysfunction is a consequence, rather than a cause, of hypertension (46, 47)

Medicinal thiols: Current status and new perspectives
