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However, RNAi therapeutics still face technical obstacles, such as achieving efficient delivery of RNAi drugs targeting organs or tissues and overcoming the off-target interactions (Persengiev et al., 2004

Polygonatum sibiricum polysaccharide inhibited liver cancer in a simulated tumor microenvironment by eliminating TLR4/STAT3 pathway

Islam, Ahmed I

8B and S9C)

The enterotrophic peptide hormone glucagon-like peptide 2 (GLP-2) was shown to abrogate OS and improve intestinal antioxidant capacity by reducing LPS-induced increases in intestinal IL-1 and oxidized glutathione levels (267) and increasing intestinal SOD activity and reduced-glutathione levels (268, 269) ( Supplementary Table 1 )

Two micrograms of total RNA were reverse-transcribed into cDNA using the GoScript TM Reverse Transcription System (Promega, USA)