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Energy production and athletic performance: By enhancing mitochondrial function, L-Carnitine injections can improve energy production and endurance, and reduce muscle fatigue and post-exercise soreness

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In this Review, Fudi Wang and colleagues discuss the link between the metabolic pathways of iron signalling and ferroptosis in the context of the cardiovascular system and describe the potential of ferroptosis inhibitors in the treatment of cardiovascular disease.

Current research priorities include large-scale studies to better understand the tissue-specific effects of NNMT inhibition and the temporal dynamics of metabolic reprogramming following treatment