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Description
Gearing and colleagues suppose that A1AT may prevent the release of MMP-12 and TNF-alpha by inhibiting the activity of both thrombin and plasmin ( The clinical-functional impact of A1AT therapy in patients with emphysema associated with A1ATD has been extensively demonstrated through numerous clinical trials

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Thamm et al

2002;282:E1139E1146

[DOI] [PubMed] [Google Scholar] 122.Marek K., Cicho N., Saluk-Bijak J., Bijak M., Miller E

Progression results in perifollicular hemorrhages, gingival hypertrophy, delayed wound healing, myalgia, muscle weakness, hyperkeratosis, weight loss, and hematological abnormalities
