glutathione s-transferase pi gstp diagram S-transferase: A versatile and dynamic enzyme GSTP1 - Wikipedia
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Copper (Cu 2+ ), as a redox-active metal, directly induces the formation of ROS at certain concentrations

The marks start as red or purple lines and, over time, become slightly depressed white streaks in your skin

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Mak TW, Grusdat M, et al

However, iron chelation can aim any protein which is iron-involving or relay on iron in the cell, including NADPH oxidase, iron-containing lipoxygenase, xanthine oxidase, etc

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