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Beyond lysosomal deacidification and inhibition of autophagosome-lysosome fusion, CQ/HCQ disrupts endolysosomal function, Toll-like receptor activation, and calcium signaling, thereby reducing pro-inflammatory cytokine production

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Curcumin may upregulate glutathione synthesis enzymes through activation of the Nrf2 antioxidant response element pathway (Balogun et al., 2003)

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doi: 10.1111/j.1475-097X.1986.tb00242.x

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It is suggested that may protect neurons from iAinduced cytotoxicity [232]

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Stop use immediately if redness, swelling, itching, irritation, depigmentation (white spots), or darkening occurs

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