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Analysis of the gene expression was performed according to the comparative CT method 50

Physiological iron uptake primarily relies on heme oxygenase (HO)-mediated iron recycling, predominantly stores in labile iron pool (LIP) by binding ferritin (Ft), and releases iron through transferrin receptor 1 [65]

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Another possibility is that peripheral NGF could enter directly to the CNS as was proposed for (Levi-Montalcini and Aloe, 1985), although the mechanisms underlying this phenomenon are unknown

For instance, overexpression of -syn increases the levels of monounsaturated fatty acids, altering the membrane lipid balance and exacerbating toxicity (139)