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Severe GI reactions (peptic ulcer, GI bleeding, and GI perforation) occurred in 0.4% to 4.6% of patients without a history of a peptic ulcer or bleed and in 2.1% to 15.4% of patients with a history of a peptic ulcer or bleed

The two-way ANOVA was applied to the log of the ARB fraction as the dependent variable

New medications: These can bring on changesfor instance, steroids, antidepressants, or antihistamines can influence fluid balance or appetite

High serum concentrations of vitamin B12 may be encountered while the clinical picture suggests B12 deficiency
Mood Changes: Increased irritability, depression, or anxiety
