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Innovative strategies in the framework of 3P medicine consider Hcy metabolic pathways as the specific target for in vitro diagnostics, predictive medical approaches, cost-effective preventive measures, and optimized treatments tailored to the individualized patient profiles in primary, secondary, and tertiary care

Data availability The datasets generated and analyzed during this study are included in the Supplementary files

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Ostrom QT, Cioffi G, Waite K, Kruchko C, Barnholtz-Sloan JS

[11] [12] [13] [14] Pharmacology [edit] Semax is a heptapeptide and synthetic analogue of a fragment of adrenocorticotropic hormone (ACTH), ACTH (4-10), of the following amino acid sequence: Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP in single-letter form)

The extensive degeneration of these DA neurons results in diminished dopamine levels within the brain, which gives rise to a spectrum of clinical manifestations, encompassing challenges in maintaining posture, the emergence of stationary tremors, a decrease in movement speed (bradykinesia) and the onset of joint stiffness reminiscent of ankylosing arthritis (49)