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The blood-brain-barrier (BBB) and tumor heterogeneity limit the treatment effectiveness of various interventions

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For at-home use, 0.250.5 mm is generally considered safe

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Curcumin (Cur)-mediated glutathione (GSH) depletion can reverse resistance, enhance the chemosensitivity of CDDP, and further improve the efficacy of platinum-containing chemotherapy in the treatment of esophageal cancer

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