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As an active form, it does not require conversion in the body and is essential for homocysteine methylation and the maintenance of healthy nerve cells

B12 levels can fluctuate, and symptoms may appear before levels fall outside the standard range

doi: 10.1016/j.jsps.2019.08.001

DISCUSSION The goal of this study was to develop an AnglV-derived molecule that retained the pro-cognitive/anti-dementia activity of AnglV and Nle'-AnglV but possessed improved pharmacokinetic properties, thus allowing it to penetrate the BBB in sufficient quantities to reach therapeutic levels in the brain

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Combination is key: The MMA test is best performed together with the serum B12 test (and possibly the holo-TC test) to get a comprehensive picture of your B12 status