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The supernatant was removed after centrifugation at 100 g for 1 min at room temperature

Only through this holistic and forward-thinking approach can we hope to develop therapies that go beyond modifying disease progression, preserving, and potentially restoring neural integrity in the human brain

RH and HH wrote the first draft of the manuscript

Arrows indicate stimulation (green), inhibition (blue), and the resulting cardiovascular effects (red)

While microglia initially respond to neuronal injury in an attempt to provide neuroprotection, their chronic activation in ALS contributes to the ongoing neuroinflammation and neurodegeneration observed in the disease 117 (Fig

PS: These thoughts are based on my experience