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These biomarkers namely plasma malodialdehyde (MDA) and blood activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx) are to be evaluated before and after the administration of the histamine H2 antagonist nizatidine alone or with either vitamin E (-tocopherol) or thioctic acid (-lipoic acid) or a combination of both

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7.4 Synergistic intervention 7.4.1 Combination of Nrf2 activators and A clearance Nrf2 activators centered on sulforaphane are driving a paradigm shift in AD treatment from traditional single-pathway approaches toward a dual-track strategy targeting both pathological clearance and ferroptosis blockade