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and E.R

Overall hair volume improved

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The most recent comprehensive synthesis is a July 2025 systematic review in the HSS Journal , the musculoskeletal journal of the Hospital for Special Surgery in New York, led by Nikhil Vasireddi at Case Western Reserve University School of Medicine

You can compare this to cyanocobalamin which requires extra steps to be used by the body assuming it actually makes it into the body through the gut

Ice crystal formation disrupts the peptides structure, and repeated freeze-thaw cycles have been observed to reduce biological activity by 20-50% (2)
