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Regarding the effects on miR-21, curcumin treatment was found to reduce miR-21 promoter activity and expression in a dose-dependent manner by inhibiting AP-1 binding to the promoter and inducing the expression of the tumor suppressor Pdcd4

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Further, toxicity evaluation was performed using Danio rerio (zebrafish) embryos as a model organism to infer potential impacts on human health [18]

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Most institutional chemical safety officers accept this format because it links the trade name used in research literature to the IUPAC string required for hazard classification databases