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Factor XIIIa inhibitors Numerous synthetic and natural factor XIII (FXIII) inhibitors have been investigated in preclinical trials and in vitro studies

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This process is likely driven by transcriptional activation of mitochondrial regulators, including PGC-1 and nuclear respiratory factor 1 (NRF-1), as shown in neuroprogenitor cells after inhibition of histone deacetylase (HDAC) [61]