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TEO, ET AL., JOURNAL OF PIGMENTARY DISORDERS 2015, 2.2

289 One limitation of ASNase therapy, which promotes tumor cell death by systematically lowering the asparagine concentration, is that it impairs ASN requirements in normal immune cells

ACC2 is a better substrate for PKA than is ACC1

doi: 10.1016/j.saa.2014.11.036

Unexpectedly, ETC function supports T cell activation and survival beyond biosynthesis
