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Loss of AhR antagonism by folate or B12 due to deficiency or activation of AhR by known agonists increases AhR activity and mimics symptoms of B9 and B12 deficiency [86]

10.1089/sur.2013.269 124 YangR

A.SiddiqueF.BibiM.et al (2023b)

Drug interactions Oral contraceptives (birth control pills) containing estrogen and progestin may increase the requirement for pantothenic acid (43)

Symptoms of B12 deficiency include: Low energy and fatigue Digestive problems Depression and moodiness Insomnia Brain fog and memory loss Anemia Reduced immune system function Tingling or numbness in the extremities Swollen tongue Loss of vision or hearing Jaundice Kidney disease Pale skin Poor circulation in the extremities If you are over age 50 and are experiencing one or more of the above symptoms, boosting your intake of B12 cannot hurt, and it may provide a safe and inexpensive solution while preventing a wrong diagnosis

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