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Dogs carrying extra weight are prone to injuries
This can aid in protecting the skin from further hyperpigmentation and promote a youthful appearance

Nrf2 has antioxidant roles, and increased HO-1 expression reduces oxidative damage and inflammation (125)

Bibcode:1975NYASA.243..104K

Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release

Methods 49 (1982) 159177
