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The new approval reinforces Krazatis potential across tumor types, the company said in a press release
[DOI] [PubMed] [Google Scholar] 254
Aspartate is an endogenous metabolic limitation for tumour growth
This recognition initiates innate immune responses and activates downstream inflammatory pathways to eliminate microbial infections and promote tissue repair (Kelley et al., 2019
It is likely that the gloB mutant was more tolerant to MG due to the functional activation of potassium efflux pumps and protective cytoplasmic acidification
M.ZhouX
