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Tissue malondialdehyde (MDA) was determined as thiobarbituric acid reactive substances (TBARS) measured colorimetrically at 532 nm 22 and tissue reduced glutathione (GSH) levels determined based on Ellmans reaction principle was read at 412 nm 23

Barish GD, Atkins AR, Downes M, et al

Presumably, selenium decreases disease severity, in part, via augmenting the expression and activity of selenoproteins, such as GPx1

Among the 40 patients evaluable for response, 18 patients met the 12-week PFS primary endpoint, with one patient achieving a PR, and 27 patients achieving SD as the best response (Scott et al., 2022)

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