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PINK1 and Parkin interact to mediate mitophagy, thereby maintaining mitochondrial homeostasis

Tesofensine is a CNS-active triple monoamine reuptake inhibitor that suppresses appetite by prolonging serotonin, norepinephrine, and dopamine signaling in hypothalamic satiety centres
On the contrary, overexpression of NCOA4 promotes the occurrence of ferroptosis (13)
10.1016/j.semcancer.2019.08.028 33 KongH.ChuQ.FangC.CaoG.HanG.LiX

doi: 10.1136/bmj.c1240
