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Currently, targeting ferroptosis can reverse chemotherapeutic resistance, which mainly consists of three pathways related to the ferroptosis mechanism, typically the GPX4-regulated pathway, the iron metabolism pathway, and the lipid metabolism pathway (42)

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Am J Med Genet B Neuropsychiatr Genet 174:93112 Hsieh MJ, Liu HT, Wang CN, Huang HY, Lin Y, Ko YS, Wang JS, Chang VH, Pang JS (2017) Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation

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