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The unique microenvironment of the renal medulla promotes hemoglobin polymerization and subsequent vaso-occlusion, leading to ischemic damage of the renal papillae

Our results in the current study show that RSL3 can target quiescent astrocyte-like glioma cells, which are relatively resistant to etoposide (Zhao et al, 2021)

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In conclusion, targeting ferroptosis offers a promising new avenue to overcome tumor drug resistance, and through continued mechanistic investigation, technological innovation, and clinical translation, ferroptosis-based therapies are poised to become a central pillar in future cancer treatment paradigms

It provides evidence that CtAtm1, a homolog of human ABCB7, facilitates the delivery from glutathione-complexed iron-sulfur clusters, enhancing our comprehension of the transport mechanisms of eukaryotic ABCB7-type proteins

Our research has supplemented the knowledge about the antioxidative role of Klotho also in heart injury
