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The actual directionality of this interaction is still not clear, however the immune response to an external pathogen could provoke unblinded oxidative stress which in turn perpetuates a steady inflammatory cascade (Maes et al

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2000;72(2 Suppl):618S23S

& McBride, S
A simple questionnaire to detect hypermobility: an adjunct to the assessment of patients with diffuse musculoskeletal pain

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