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Another example is that by gut microbiota fermenting dietary fiber into short-chain fatty acids

The pathological features of AD include -amyloid plaques, neurofibrillary tangles, and neuronal loss

Low glutathione impairs thermotolerance As the steady-state level of extractible reduced glutathione is mostly affected under high temperature, we studied the response to high temperatures of the cadmiumsensitive2 ( cad2 ) and phytoalexin-deficient mutant ( pad2-1 ) mutants, which contain low level of glutathione due to impaired glutathione synthesis capacities (Howden et al., 1995

TRH is mainly expressed in the hypothalamus of fish, amphibians, birds and mammals, and has been detected in a number of peripheral tissues in reptiles (74)

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Individual geroprotective compounds fail to address the complexity, interconnectedness, and dynamic nature of biological systems, limiting success in significantly extending lifespan and improving health