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Irrespective of the knowledge that the effects of neuronal signalling in the nervous systems may include a number of different receptor subtypes of both the nicotinic and the muscarinic receptors, this complexity is generally overlooked when assessing the mechanisms of action of pharmaceuticals

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10.3390/cells11050844 98 LiuT.LvY

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In tumor cells, PKM2 is present mainly as the low-activity dimeric form, which leads to increased accumulation of diverse glycolytic intermediates required for macromolecule biosynthesis and thus promotes cancer proliferation (Zhao et al., 2022)
