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, a hypothesis was proposed which linked chronic low dose exposure to POPs to global hypomethylation, as a consequence of GSH depletion

Who Should Think About Including Glutathione in Their Daily Routine
Molecular Mechanisms of Nitric Oxide in Cancer Progression, Signal Transduction, and Metabolism

10.2147/OTT.S157707 174 XiaQ.LiuY

The synthesis of these -glutamyl peptides by -GCS and GS appears more likely to occur when cells are under pathological conditions that feature a Cys deficiency (Figure 7)
A slight but significant increase of coumarin-6 uptake by ischemic brains of mice was observed with GSH coated PLGA-PEG nanoparticles when compared with non-GSH coated PLGA-PEG nanoparticles [51]
