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Trends Immunol (2018) 39:67796

Warren CA, Guerrant RL

Quais as principais diferenas entre termognicos e L-carnitina

H., Rush, A

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In an experimental model of abdominal aortic aneurysm, topiramate markedly downregulated pro-inflammatory M1 macrophage activity, reduced the expression of TNF-, IL-1, and matrix metalloproteinase-9, and promoted a phenotypic shift of macrophages from M1 to M2, thereby mitigating pro-inflammatory activity and enhancing tissue repair processes ( These studies collectively suggest that topiramate exerts significant neuroprotective effects across various pathological models through its potent anti-inflammatory properties