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In yeast, mitochondria-associated degradation (MAD)analogous to ERADensures proteostasis by extracting, ubiquitinating, and degrading misfolded mitochondrial proteins in the cytosol

Mitoquinone ameliorated airway inflammation by stabilizing -catenin destruction complex in a steroid-insensitive asthma model

Variations in detoxification enzymes, DNA repair pathways, and immune regulation influence how individuals metabolize and respond to carcinogens [264]

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Under the influence of a leaky epithelial barrier, the immune system is locally activated and inflammation develops, which can be transmitted via immune cells and the cytokines they secrete to other systems and organs

Quorum-sensing Salmonella selectively trigger protein expression within tumors