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8 Therapeutic perspective targeting propionate metabolism in PA Since chronically elevated propionate is a key factor in the neurological dysfunction associated with PA, treatment strategies should focus on reducing propionate synthesis and enhancing its metabolic disposal
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The modulation of dopamine levels may occur through enhanced GSH production, impacting striatal dopamine levels via GSH influence on NMDA and non-NMDA glutamate receptors [143]
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If you have a small area, 20 to 25 percent may make a really big difference or a small difference
