melanotic macule/nevus Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Nevus spilus (Speckled Lentiginous Nevus,

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The protein concentrations of the samples were determined using a Protein Assay Bicinchoninate Kit (Nacalai Tesque, Inc., Kyoto, Japan)

Histopathologically, both types may be junctional, compound or intradermal (intra mucosal), but CMN generally shows a diffuse band-like infiltrate of melanocytes streaming through collagen bundles rather than the classic cell nest formation of acquired nevus [1, 5]

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There is little difference in the histopathologic features of the original biopsy and the recurrent lesion