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For cohort 1, the ODB database was used to identify patients who were prescribed vitamin B12 injections

"Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans." Journal of Endocrinology and Metabolism 3.1-2 (2013): 7-15

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I had all these problems before starting methyl-B12 so they weren't new, but they got many times worse than usual once I started the B12
Indeed it has been hypothesized that depression and vascular disease may be different manifestations of the same genetic substrates 79

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